Author: Rachel Kim
Perspective
Advancements in Vaccine Technology for Universal Influenza Vaccines
Rachel Kim*
Division of Virology, University of Washington, Seattle, WA, USA
Available online: 11 Feb 2013
Abstract
Seasonal influenza vaccines offer limited protection due to the rapid antigenic drift of influenza viruses, necessitating annual reformulation. The threat of influenza pandemics further underscores the urgent need for broadly protective, or “universal,” influenza vaccines. This perspective article explores the cutting-edge advancements in vaccine technology aimed at achieving this goal. We discuss innovative approaches targeting conserved viral antigens, novel delivery systems, and immunomodulatory strategies designed to elicit durable and cross-reactive immune responses against diverse influenza strains. The successful development of a universal influenza vaccine would represent a paradigm shift in influenza prevention and pandemic preparedness.
